hrp0095t15 | Section | ESPE2022

Secondary Oxidized DEHP Metabolites May Participate in the Progression from Isolated Premature Thelarche to Central Precocious Puberty or Early Puberty

Zheng Xiuxin , Su Zhe

Objective: Urine phthalic acid esters (PAEs) are one of estrogen-mimetic EDCs. Many studies have suggested that urinary phthalic acid esters (PAEs) are closely related to central precocious puberty (CPP) and isolated premature thelarche (IPT), but there is no study between urinary PAEs and the progression of IPT. This study is to explore the influence of PAEs on the progression of IPT to CPP or early puberty (EP).Methods:</strong...